ヘルミーナとクルス ~リリーのアトリエ もう一つの物語
Initial Release date: December 20, 2001 (JP)
Platform: Sony PlayStation 2
Artist: Isaemon Yamagata/山形伊佐衛門
The young alchemist Hermina has created an homunculus by the name Culus. The homunculus cannot show many expression or say many words, but Culus learns new words from the people of Salburg.
Eventually, the player can use the words Culus have learnt to become Hermina's friend. (via Atelier Wikia)